Druiddroid
OG
this is a pretty fail count tbh, considering this is actually 140
Bragh said:GeneID: 154 updated 17-Dec-2009
[Top][Help]Summary
Official Symbol
ADRB2
provided by HGNC
Official Full Name
adrenergic, beta-2-, receptor, surface
provided by HGNC
Primary Source
HGNC:286
See related
Ensembl:ENSG00000169252; HPRD:00187; MIM:109690
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BAR; B2AR; ADRBR; ADRB2R; BETA2AR; ADRB2
Summary
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq]