You can make almost anything work in this bracket if you're good at the comp/classes you play. Thing is you'll still be at a dissadvantage against any comp containing r/m/p most times.
That said obviously a sick mage would always work in 2s. Wouldnt go healer/enha because even with synapse your dmg would be too shit to kill anyone. In 3s like i said, most comps will work with good players.